A correlation may exist between the diabetes drug metformin and birth abnormalities, according to a study conducted by Stanford Medicine researchers and their colleagues in Denmark.
Published in the journal Annals of Internal Medicine, the research does not confirm a direct cause and effect between the drug and birth defects, but statistics from an extensive analysis of health records did show a relationship between the two.
Researchers tracked more than 1 million births in Denmark between 1997 and 2016, and they discovered a link between the use of metformin during sperm development and genital birth defects in boys.
The birth defects were found only in boys, and the fathers tracked in the study were more likely to have girls in comparison to the general population. The cause of the link between the drug and men's reproductive health has yet to be determined.
Metformin is an increasingly popular drug for treating type 2